Time;Event

08:00–15:00;Meeting of participants, transfer from Knevichi airport to Russky Island. Check-in at the hotel 15:00–17:00;Registration 17:00–18:00;Official opening 18:00–21:00;Social program: Welcome reception

Time;Event

8:30–9:00;Registration 9:00–11:30;Session: Genetic and Cellular Technologies ;Plenary lecture: Stepanov Grigory ;Plenary lecture: Baklaushev Vladimir ;Sponsors’ talk (Bioline). The Future is already here. Multispectral flow cytometry and optical microscopy beyond the limits of the diffraction limit. ;Yusubalieva Gauhar: "Optimization of Glioblastoma Mouse Orthotopic Xenograft Models for Translational Research" ;Nushtaeva Anna: "Heterotypic tumor spheroids are a cellular model to study tumor microenvironment biology" ;Dashinimaev Erdem: "Direct differentiation of induced human pluripotent stem cells by self-complimentary adeno-associated viral vectors" ;Sponsors’ talk (LLC “Lacopa”). Novel approaches to live-cell imaging: challenges and solutions. ;Sudina Anastasia: "Therapeutic efficacy of glial progenitor cell transplantation in a rat model of traumatic brain injury" 11:30–11:50;Coffee break 11:50–14:05;Session: Oncobiology and Molecular Diagnostics of Tumors ;Plenary lecture: Sergiev Petr ;Plenary lecture: Kichkaylo Anna ;Plenary lecture: Buzdin Anton ;Nutan Rakeshkumar Shukla: "Targeted Isolation of Circulating Tumor Cells (CTCs) Using Aptamer-Functionalized Biofilms Integrated within a Microfluidic Chip" ONLINE ;Bryushkova Ekaterina: "Case report: longitudinal tracking of T-cell clonotypes in an NSCLC patient with sustained remission" ;Orlov Pavel: «First case of sequencing registered onco-panel libraries with error correction code». Talk supported by Diaem. ;Luzan Natalia: "Development of DNA aptamers for visualization of glial brain tumors" ;Ibragimova Marina: CNA markers of preoperative chemotherapy efficacy in luminal B breast cancer ;Kamentseva Rimma: "EGFR family expression profile in cultured human mesenchymal stromal cells in comparison to tumor-derived cell lines" 14:05–15:00;Lunch 15:00–17:00;Young Scientists Forum "Future of Biomedicine: Young, FOBY" 17:00–17:20;Coffee break 17:20-20:30;Session: Structure and Functions of Biomolecules ;Plenary lecture: Yanshole Vadim ;Plenary lecture: Bocharov Eduard ;Plenary lecture: Konevega Andrey ;Plenary lecture: Boiko Konstantin ;Burtseva Anna: "Structure of a bundle-shaped phycobilisome" ;Shugoreva Irina: "Elucidating the Structural Organization of Aptamers through Molecular Modeling and Synchrotron Radiation" ;Goncharuk Marina: "Cell-free synthesis of properly folded proteins as a prospective tool for structural and biomedical applications" ;Lomzov Alexander: "Phosphoramidate Benzoazole Oligonucleotides (PABAO): Synthesis, Properties, and Applications" ;Vasilieva Svetlana: "New phosphoramide azole oligonucleotides (PABAOs) - candidates for the therapeutic nucleic acids role" ;Mungalov Roman: "Landscape of antigenic specificity of T-cell receptors" ;Goncharuk Sergey: "Transmembrane domains of neurotrophin receptors as a target for antidepressants" ;Bashkirov Pavel: "Single molecule characterization of dynamic protein interactomes via membrane deformations" ;Anisenko Andrey: "Mass spectrometry-based approaches to identify cellular proteins involved in HIV-1 postintegration DNA repair" ;Verlov Nikolay 21:00–23:00;Social program: Evening tour of Vladivostok

Time;Event

9:30–12:00;Session: Biomedical Chemistry ;Plenary lecture: Skorb Ekaterina ;Plenary lecture: Dr. Ashaben Mehulkumar ;Markov Oleg: "Cholesterol- and spermine-based cationic liposomes as highly efficient carriers for mRNA vaccines" ;Dmitrienko Elena: "The influence of different types of internucleotide phosphate modifications on the properties of designed oligonucleotides" ;Sponsors’ talk ;Berlina Anna: "Interaction of E. coli cell wall with various biomolecules and its application in analytical systems" ;Serchenya Tatyana: "Isothermal recombinase polymerase amplification and immunodetection of DNA of pathogenic microorganisms" ;Maria Nikitina: "Carbon black nanoparticles for the laboratory diagnostic test systems development" ;Solyev Pavel: "Employing Cys-/Met-metabolism enzymes for targeting bacteria, fungi and cancer" 12:00–12:20;Coffee break 12:20–14:00;Young Scientists Forum "Future of Biomedicine: Young, FOBY" 14:00–15:00;Lunch 16:00–22:00;Social program: Sea cruise

Time;Event

9:00–11:30;Session: Molecular Medicine and Medical Genetics ;Plenary lecture: Lebedev Igor ;Plenary lecture: Severinov Konstantin ;Plenary lecture: Skoblov Mikhail ;Egorov Alexander: "Gene Therapy for Obesity Treatment" ;Andreev Dmitry: "Alternative translation initiation sites in human mRNAs that give rise to novel proteoforms" ;Smolnikova Marina: "Pathogenesis of asthma in children: new markers of the disease" ;Sparber Petr: "The Russian collection of biological samples of hereditary diseases: a unique resource for precision medicine" ;Borovikov Artem: "Challenges and biobank-based solutions for undiagnosed monogenic diseases" ;Kechin Andrey: "eLaRodON: identification of large genomic rearrangements in Oxford Nanopore sequencing data" ;Kozhevnikova Elena: "Disruption of cytoskeletal dynamics underlies dysfunction of the intestinal epithelial barrier in chronic colitis" 11:30–11:50;Coffee break 11:50–14:10;Session: Molecular Medicine and Medical Genetics ;Plenary lecture: Naumenko Vladimir ;Plenary lecture: Rubtsova Maria ;Plenary lecture: Battulin Nariman ;Sponsors’ talk ;Chaprov Kirill: "Compensatory potential of synuclein family proteins in an MPTP-induced parkinsonism model with conditional alpha-synuclein inactivation" ;Ilchibaeva Tatyana ;Murtazina Aisylu: "The evolving role of physicians in the diagnostics of genetic neuromuscular disorders" ;Atamanyuk Natalia: "Molecular mechanisms of early and late consequences of gamma irradiation of the central nervous system" ;Grekhnev Dmitry: "Crosstalk between calcium signaling and cGAS-STING pathway in neurodegeneration and neuroinflammation" ;Bazovkina Daria: "Effect of the C.886C>T mutation in the tyrosine hydroxylase gene on brain dopamine system and behavior in mice" 14:10–15:10;Lunch 15:10–17:30;Session: Synthetic Biology and Biotechnology ;Plenary lecture: Gelfand Mikhail ;Plenary lecture: Kumeyko Vadim ;Plenary lecture: Lavrik Inna ;Yesmagambetov Ilyas: "AAV vectors for gene therapy and prevention of infection diseases" ;Vildanova Maria: "Effect of abscisic acid on the human skin cells cultivated in 2D- and 3D conditions" ;Krasitskaya Vasilisa: "Analytical tools based on coelenterazine-dependent luciferases" ;Orlova Nadezhda: "Tissue engineering substitution of different urinary bladder volumes in experiment" ;Prokhorova Daria: "The effect of phosphorilguanidine modifications in chimeric guide RNAs on CRISPR/Cas9 activity" ;Malbakhova Inna: "Hydrogel scaffolds with immobilized bacteriophages as promising materials for the treatment of antibiotic-resistant wound infections" 17:50–20:00;Social program: Excursion to the Primorsky Aquarium

Time;Event

9:00–11:00;Young Scientists Forum "Future of Biomedicine: Young, FOBY" 11:00–11:20;Coffee break 11:20–14:40;Session: Biomolecules and Drug Development ;Plenary lecture: Silantyev Vladimir ;Plenary lecture: Kozlov Sergey ;Plenary lecture: Kokoev Leonid ;Plenary lecture: Gushchin Ivan ;Slonova Daria: "Antibacterial and wound-healing effects of interferon-α2b and endolysin GRC-ML07 in an immunosuppressed mouse model" ;Ryabchevskaya Ekaterina: "The development of SARS-CoV-2 recombinant proteins for subunit vaccine and analysis of its antigenic properties with immune sera from Wuhan-, Delta- or Omicron-recovered donor" ;Kozlovskaya Lyubov: "In vitro systems for phenotypic screening of small molecules against RNA viruses" ;Osolodkin Dmitry: "Novel Antiviral Chemotypes from the Catalogues of Commercially Available Compounds" ;Proshin Pavel: "Targeted Drug Delivery via Biodegradable Multilayered Films: PLACE Technology for Controlled Local Release" ;Andreev Yaroslav: "TRPV1 channel modulators for the treatment of neurodegenerative diseases" ;Kalyuta Tatyana: "Comparative structural and functional analysis, efficacy, and safety of systemic non-opioid analgesics registered in Russia as a basis for identifying new molecular entities" ;Kasheverov Igor: "Ligands of nicotinic acetylcholine receptors as a basis for the development of potential drugs" ;Sachivkina Nadezhda: "Reduced virulence of mutant strains of Cryptococcus neoformans in vivo and in vitro" 14:40–15:40;Lunch 15:40–18:40;Session: Personalized Therapy in Oncology ;Plenary lecture: Litvyakov Nikolay ;Plenary lecture: Grigoryeva Elvira ;Kuligina Elena: "Results of Phase I Clinical Trials of Oncolytic Virus VV-GMCSF-Lact" ;Dymova Maya: "Aptamers as tools for increasing the antitumor efficacy of the oncolytic virus VV-GMCSF-Lact" ;Koshmanova Anastasia: "Aptamers for Glial Tumor Targeted Therapy" ;Sleptsova Ekaterina: "Photodynamically induced glioma cell death as a basis for antitumor immunotherapeutic strategy" ;Yagolovich Anna: "Dual targeting of malignant cells and tumor microenvironment with multispecific fusion proteins binding DR5, VEGFR, and FGFR Receptors" ;Malyuchenko Natalia: "Effect of synthetic and natural epigenetically active compounds on PARP1 functions as a target for anticancer therapy" ;Shtam Tatyana: "Plant Vesicles — Effective Delivery Systems for Therapeutic Proteins to Activate Antitumor Immune Response" ;Tsyganov Matvey: "The role of alterations in the homologous recombination system genes in the treatment of patients with non-small cell lung cancer" ;Miroshnichenko Svetlana: "Exploring the best-responding types of malignancies for the microRNA-targeted mesyl oligonucleotides" ;Patutina Olga: "Antitumor potential of microRNA-targeted therapy in colorectal cancer" ;Styazhkina Elena: "Liposomal Targeted Nanostructures for Radionuclide Cancer Therapy" 19:30-24:00;Social program: Gala dinner at the "Cruise" restaurant, Shamora Bay

Time;Event

9:30–11:00;Forum of young scientists "Future of Biomedicine: Young, FOBY" 11:00–11:20;Coffee break 11:20–13:00;II School-workshop "Genetic and cellular technologies in scientific and clinical practice" 13:00–14:00;Lunch 14:00–18:00;II School-workshop "Genetic and cellular technologies in scientific and clinical practice"

Time;Event

08:00–17:00;Transfer from Russkiy Island to Knevichi airport